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The Japanese have occupied part of North China including an area that includes an American missionary compound where Shirley lives with her husband Caleb and son Charles, when Charles is reported killed on a visit to outlying churches. The Japanese clash with the Chinese armies–both Nationalists and Communists–and the war spills over into the lives of the compound. Shirley, a nurse, helps treat the wounded Chinese, running afoul of the Japanese. Numerous conflicts ensue and all of their lives are endangered.